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LEGAL NOTICE
What exactly is Clenbuterol and what is this supplement used for? The definition of Clenbuterol is a synthetic stimulant compound that activates beta-2 adrenergic receptors in the body to promote weight loss.
Clenbuterol is a bronchodilator used worldwide to treat high blood pressure, cardiovascular shock, asthma, migraines, anaphylactic shock, and arrhythmia.
As a bodybuilding supplement, it is also taken for weight loss, diet and fat burning results.
Clen is well defined for being able to promote fat loss while preserving muscle tissue in an anti-catabolic fashion.
It is also commonly used by female celebrities so they can achieve a toned look and eliminate unwanted body fat.
This substance often comes in 20 mcg tablets, and it is also distributed in syrup and injection form.
It is often confused with a steroid, but is actually a sympathomimetic because it affects the sympathetic nervous system by interacting with adrenoceptors. Click here to buy legal Clenbuterol online, without a prescription.
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There are nine types of receptors in the body that have their own subcategory number. Clenbuterol affects only one of the three subsets of beta-receptors (beta-2).
Defined as a beta-1 stimulant, Clenbuterol relieves bronchial and arterial obstructions and has little or no side effects to the heart (as opposed to nonselective beta agonists).
Clenbuterol research experiments have proven the drug to be a highly efficient bronchodilator.
It’s easy to use because it only takes one dose per day (Actually, it lasts 34 hours in the body) to maintain steady levels of it in the blood.
Also, there are virtually no consumer complaints when Clenbuterol is taken correctly.
Although Clenbuterol is not approved in the United States, it is still used in a lot of other countries, which makes it easy to buy this drug online from places like Europe, India, Mexico or South Africa.
It is assumed that the large existence of effective asthma medications already on the market is the culprit behind Clenbuterol not being available in the US, making it not cost effective to submit Clenbuterol for FDA approval.
For now, US consumers have to purchase the substance through international sources.
Animal research has proven that Clenbuterol has effective anabolic qualities.
This substance is also fits the definition of a thermogenic and is a beta-2 agonist that affects fat cells by transforming them into free fatty acids. Because of these two qualities, this drug is an ideal choice for athletes.
People using Clenbuterol desire more muscle and less fat. This is one of the reasons it is commonly used by women who want to slim down.
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Because the Medicine and Science in Sports and Exercise printed a review in August of 1995 that pointed to the fact that the research is primarily the product of animal testing, many people doubt whether Clenbuterol is effective in humans in any way.
We know that humans have less of the receptors that Clenbuterol stimulates, compared to animals.
However, there really is no doubt that Clenbuterol is working when you first take it. You will immediately notice the stimulating effects of this drug.
There are plenty of users who attest to its success in increasing muscle mass, and there are some that say using the drug is not worth their time.
These conflicting claims can confuse people into thinking Clenbuterol is not worth trying.
Insomnia, sweating, increased blood pressure, shaking hands, and nausea are potential side effects of taking Clenbuterol that last no more than a week as the body gets adjusted to the compound being in the body.
To decrease the likelihood of side effects, many start with very low doses and gradually increase to the normal dose.
Men generally take 2 – 8 tablets per day while women take 2 – 4 tablets a day.
Clenbuterol raises the body’s temperature by at least a half degree. The reason why is because the body is converting fat into energy.
Don’t worry, you won’t really notice the body temperature change.
Also, keep in mind that this drug can’t be used for excessively long periods of time or else the effectiveness will gradually wear off as the body becomes even more adjusted to the compound.
SAFETY WARNINGA recommended time length is 4-6 weeks. To determine when Clenbuterol is no longer working in your body, just check to see if your body temperature has returned to normal.
You’re going to have to stop taking it and retry it after a few weeks have gone by to regain the effect of the compound.
This is when it is a good idea to cycle with Tren or other anabolics.
At this point, increasing the dose won’t do any good until your body has rested from using the substance.
If you try to increase the dose higher than this, you will only increase the risk of side effects without improving your results at all.
Athletes agree that combining Clenbuterol with thyroid hormones (like Cytomel) allows it to burn even more fat without even having to change the normal diet.
Growth hormone therapy utilizes the aforementioned combination to enhance the thermogenic and anabolic nature of the drug.
Clenbuterol is commonly used in combination with anabolic steroids during an athlete’s or bodybuilder’s ‘cutting’ cycle.
One of the most typical cycles is testosterone, Winstrol, and Clenbuterol.
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- Wingert WE, Mundy LA, Nelson L, Wong SC, Curtis J. Detection of clenbuterol in heroin users in twelve postmortem cases at the Philadelphia medical examiner’s office. J Anal Toxicol. 2008 Sep;32(7):522-8.
- Thevis M, Thomas A, Beuck S, Butch A, Dvorak J, Schänzer W. Does the analysis of the enantiomeric composition of clenbuterol in human urine enable the differentiation of illicit clenbuterol administration from food contamination in sports drug testing?” target=”_blank”>Rapid Commun Mass Spectrom. 2013 Feb 28;27(4):507-12. doi: 10.1002/rcm.6485.
- Soppa GK, Lee J, Stagg MA, Felkin LE, Barton PJ, Siedlecka U, Youssef S, Yacoub MH, Terracciano CM. Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure. Cardiovasc Res. 2008 Mar 1;77(4):695-706. doi: 10.1093/cvr/cvm106. Erratum in: Cardiovasc Res. 2008 Oct 1;80(1):159.
- Ramos BP, Colgan LA, Nou E, Arnsten AF. Beta2 adrenergic agonist, clenbuterol, enhances working memory performance in aging animals. Neurobiol Aging. 2008 Jul;29(7):1060-9.
- Thompson JA, Mirza MH, Barker SA, Morgan TW, Bauer RW, McConnico RS. Clenbuterol toxicosis in three Quarter Horse racehorses after administration of a compounded product. J Am Vet Med Assoc. 2011 Sep 15;239(6):842-9. doi: 10.2460/javma.239.6.842.
- Shimamoto S, Ijiri D, Nakashima K, Kawaguchi M, Ishimaru Y, Furukawa A, Ohtsuka A. Clenbuterol changes phosphorylated FOXO1 localization and decreases protein degradation in the sartorius muscle of neonatal chicks. Biosci Biotechnol Biochem. 2016 Aug;80(8):1499-504. doi: 10.1080/09168451.2016.1158629.
- Li L, Zhang J, Tang C, Zhao Q. Accumulation of clenbuterol residues in the hair of Chinese Simmental beef cattle during and after treatment. J Anal Toxicol. 2014 Jan-Feb;38(1):52-6. doi: 10.1093/jat/bkt095.
- Ishimaru Y, Ijiri D, Shimamoto S, Ishitani K, Nojima T, Ohtsuka A. Single injection of the β2-adrenergic receptor agonist, clenbuterol, into newly hatched chicks alters abdominal fat pad mass in growing birds. Gen Comp Endocrinol. 2015 Jan 15;211:9-13. doi: 10.1016/j.ygcen.2014.12.002.
- Lovitz ES, Thompson LT. Memory-enhancing intra-basolateral amygdala clenbuterol infusion reduces post-burst afterhyperpolarizations in hippocampal CA1 pyramidal neurons following inhibitory avoidance learning. Neurobiol Learn Mem. 2015 Mar;119:34-41. doi: 10.1016/j.nlm.2014.12.004.
- Lovitz ES, Thompson LT. Memory-enhancing intra-basolateral amygdala clenbuterol infusion reduces post-burst afterhyperpolarizations in hippocampal CA1 pyramidal neurons following inhibitory avoidance learning. Neurobiol Learn Mem. 2015 Mar;119:34-41. doi: 10.1016/j.nlm.2014.12.004.
- Sumi K, Higashi S, Natsume M, Kawahata K, Nakazato K. Temporal changes in ERK phosphorylation are harmonious with 4E-BP1, but not p70S6K, during clenbuterol-induced hypertrophy in the rat gastrocnemius. Appl Physiol Nutr Metab. 2014 Aug;39(8):902-10. doi: 10.1139/apnm-2013-0431.
- Wang P, Wang R, Zhang W, Su X, Luo H. Novel fabrication of immunochromatographic assay based on up conversion phosphors for sensitive detection of clenbuterol. Biosens Bioelectron. 2016 Mar 15;77:866-70. doi: 10.1016/j.bios.2015.10.053.
- Groot MJ, Lasaroms JJ, van Bennekom EO, Van Hende J, Nielen MW. Possible contamination with clenbuterol from treated veal calves to untreated pen mates. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(6):1063-7. doi: 10.1080/19440049.2013.781276.
- Liu P, Xiang JZ, Zhao L, Yang L, Hu BR, Fu Q. Effect of beta2-adrenergic agonist clenbuterol on ischemia/reperfusion injury in isolated rat hearts and cardiomyocyte apoptosis induced by hydrogen peroxide. Acta Pharmacol Sin. 2008 Jun;29(6):661-9. doi: 10.1111/j.1745-7254.2008.00794.x.
- Manini A, Labinson RM, Kirrane B, Hoffman RS, Rao R, Stajic M, Nelson LS. A novel neuromuscular syndrome associated with clenbuterol-tainted heroin. Clin Toxicol (Phila). 2008 Dec;46(10):1088-92. doi: 10.1080/15563650802139948.
- Gonçalves DA, Silveira WA, Lira EC, Graça FA, Paula-Gomes S, Zanon NM, Kettelhut IC, Navegantes LC. Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E123-33. doi: 10.1152/ajpendo.00188.2011.
- Downie D, Delday MI, Maltin CA, Sneddon AA. Clenbuterol increases muscle fiber size and GATA-2 protein in rat skeletal muscle in utero. Mol Reprod Dev. 2008 May;75(5):785-94.
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